This work was carried out at the animal health veterinary clinic, located on Cuauhtémoc avenue, Colonia La Rivera, in the city of Tuxpan de Rodríguez Cano, Veracruz, Mexico, during the period of October 2019 - March 2020. Aiming to determine the prevalence canine Ehrlichiosis, for which 30 canine E. canina serotypes were identified. For this evaluation, the AB GENOME kit was used, which was based on an indirect ELISA test in canines with apparent symptoms of the disease. The data were processed in the SPSS version 10 statistical package and the differences between treatments were detected by Duncan's test, the level of significance was 95% taking into account the variables of sex, age and race. The results indicated 23% of positive cases of the canines exposed to E. canis and 7 negative cases with a prevalence of 76.66%. According to the results obtained that were based on the association that existed between the presence of antibodies against E. canis, with age, race, sex, it was determined that there is no association between the presence of antibodies against E. canis and none of the variables described above.