Irritable bowel syndrome and mental health: An overview
CMR College of Pharmacy, Kandlakoya, Medchal, Hyderabad, Telangana, India.
Review Article
Open Access Research Journal of Biology and Pharmacy, 2023, 09(02), 067–072.
Article DOI: 10.53022/oarjbp.2023.9.2.0062
Publication history:
Received on 20 October 2023; revised on 07 December 2023; accepted on 10 December 2023
Abstract:
Irritable bowel syndrome (IBS) is the most common condition of gut-brain connections, affecting 10-15% of the general population globally. IBS is classified as a functional gastrointestinal disorder and results from dysregulation of central and enteric nervous system interactions. furthermore, recent studies indicate that psychological distress may alter systemic and gut immunity, which is increasingly recognized as a pathophysiologic feature of IBS. The diagnosis is currently limited to recurrent abdominal pain associated with altered bowel habits, but the majority of patients also experience non-painful abdominal discomfort, linked to psychiatric conditions (anxiety and depression), along with additional symptoms associated with visceral and somatic pain. Due to the varied nature of the illness and the range of medicines available, clinicians may struggle to determine the best method for managing individuals with IBS. Psychosocial factors are closely related to their gut physiology, associated cognitions, symptom manifestations, and illness behavior. As a result, although symptoms may improve with pharmacologic treatment, to provide the best care, the physician must be aware of the psychosocial problems that IBS patients experience and establish positive patient-physician relationships.
Keywords:
Irritable bowel syndrome; Gut-brain connection; Psychosocial factors; Psychiatric conditions.
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Copyright © 2023 Author(s) retain the copyright of this article. This article is published under the terms of the Creative Commons Attribution Liscense 4.0