Phytochemical and toxicity test of secondary metabolites extracted from Streptomyces bacteria against Anopheles larvae in Lampung, Indonesia
1 Department of Medical Laboratory Techniques, Politeknik Kesehatan Kemenkes Tanjungkarang, Indonesia.
2 Department of Biology, Faculty of Mathematics and Sciences, Universiy of Lampung, Bandar Lampung, Indonesia.
Research Article
Open Access Research Journal of Biology and Pharmacy, 2022, 06(02), 035-041.
Article DOI: 10.53022/oarjbp.2022.6.2.0084
Publication history:
Received on 16 October 2022; revised on 24 November 2022; accepted on 26 November 2022
Abstract:
This research carried out to determine the chemical composition of Streptomyces sp extract and the toxicity activity of the secondary metabolite against mosquito larvae of Anopheles sundaicus. By using a completely randomized design (CRD), the study was conducted from June to November 2021. The results of the chemical test showed that the isolate of Streptomyces bacteria contains alkaloids, flavonoids and terpenoids. The results of the larvicidal test of the extracts against Anopheles larvae were significantly different (p<0.05) in the number of mortalities between concentrations. The maximum mortality was shown by the extract at a concentration of 500 ppm with an exposing time of 48 hours. In conclusion, the secondary metabolite of Streptomyces bacteria is potential as a larvicide candidate for Anopheline mosquitoes.
Keywords:
Toxicity test; Phytochemical Test; Streptomyces; Larvicides; Anopheles larvae; Anpheles sundaicus
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