Seroprevalence of syphilis among human immunodeficiency virus seropositive clients in Ndagiri, Gwagwalada Abuja Nigeria
1 Medical laboratory service university of Abuja Teaching Hospital Gwagwalada, Abuja Nigeria.
2 School Medical Laboratory Science, plateau State College of Health Technology pankshin Jos Nigeria.
3 Department of epidemiology and evidence-based medicine, F, F, Erisma Institute of Public Health, I. M. Sechenov First Moscow State Medical University, Russia.
Research Article
Open Access Research Journal of Biology and Pharmacy, 2023, 08(02), 017–022.
Article DOI: 10.53022/oarjbp.2023.8.2.0026
Publication history:
Received on 20 June 2023; revised on 04 August 2023; accepted on 07 August 2023
Abstract:
Syphilis facilitates both HIV transmission and acquisition, reflecting the complex interplay between the two infections. Scarce information exists regarding syphilis epidemiology in Nigeria. Thus, this study determined the sero-prevalence of syphilis among people attending ART Clinic Ndagiri primary health care centre Gwagwalada area of Federal Capital Territory Abuja Nigeria. A cross-sectional study was conducted from July to September, 2019. 290 HIV–infected participants were studied; but individuals under 20 years of age and above 60 years were excluded. Structured questionnaires were used to collect data on socio-demography. Moreover, blood samples were collected from all participants and screened for syphilis using rapid test kit, and those found sero-positive were confirmed using Polymerase Chain Reaction assay (PCR).Out of 290 samples collected and analyzed, result shows the general prevalence of 0.35% among ART patients in UATH. In regards to sex, 0.52% prevalence was recorded with a significant P-value of 0.04. 0.65% prevalence was however recorded among age group 31-40 with an insignificant P-value 0.09. A higher prevalence was found among singles with 1.24% which was still insignificant with a P-value of 0.095. Conclusively, despite this low prevalence recorded, awareness campaigns, Syphilis screening and testing service with HIV/AIDS care is critically needed which could limit the clinical consequences of untreated Syphilis as well as its adverse impact on HIV transmission.
Keywords:
Seroprevalence; Syphilis; Human; Immunodeficiency; Seropositive; Antiretroviral
Full text article in PDF:
Copyright information:
Copyright © 2023 Author(s) retain the copyright of this article. This article is published under the terms of the Creative Commons Attribution Liscense 4.0