Type 2 diabetes mellitus: Prevalence and risk factors associated, among patients at Franceville Amissa Bongo regional Hospital, Gabon

Thiéry Ndong Mba 1, 3, *, Evelyne Avoune Epse Ella Missang 2, Cédric Sima Obiang 3, Michelle Claude Pambo Mihindou 3, Aldrain Jonas Ewore Ntoutoume 1, Ulrich Lowens Onkassa Sah 1, Hilaire Moundounga Kenguele 1 and Louis-Clément Obame Engonga 3

1 Molecular and Cellular Biology Laboratory (MCLAB) University of Science and Technology of Masuku (USTM), Pbox 943, Franceville, Gabon.
2 Amissa Bongo regional Hospital, Pbox 940 Franceville, Gabon.
3 Research Laboratory in Biochemistry (RELABIO), University of Sciences and Techniques of Masuku (USTM), Pbox 943 Franceville, Gabon.
 
Research Article
Open Access Research Journal of Biology and Pharmacy, 2024, 11(01), 001–012.
Article DOI: 10.53022/oarjbp.2024.11.1.0016
Publication history: 
Received on 13 March 2024; revised on 24 April 2024; accepted on 27 April 2024
 
Abstract: 
Introduction: To assess the type 2 diabetes mellitus prevalence and risk factors associated, among patients, at Franceville Amissa Bongo regional Hospital Gabon, A prospective and cross-sectional study was carried out between June and September 2023.
Materials and Methods: Blood glucose was measured using blood drawn from each participant, according to American Diabetes Association standards. As elsewhere, correlations between type 2 diabetes mellitus prevalence and the variables obtained, were carried out using R software version 3.6.1. Odds ratios were calculated within a 95% interval, and results were considered significant when the p-value ≤ 0, 05.
Results: Blood samples from 328 people, with a mean age of 48.24 ± 13.8 years, were collected for this study. The type 2 diabetes mellitus prevalence was 13.72% (95% CI: [0.10- 0.18]), (n=45). After univariate analysis, adjustment of variables by binary multivariate logistic regression, indicated female gender (Ajusted OR = 0.53; 95% CI [1.52; 39.41] p = 0.014*), cohabiting (Ajusted OR = 92.73 ; 95% CI [2.9; 29.05] p = 0.010*), inactive (Ajusted OR = 9.17; 95% CI: [1.11; 75.05] p = 0.040*), overweight/obese (Ajusted OR = 0. 017; 95% CI: [0.002; 0.18] p = 0.010*), a family history of type 2 diabetes mellitus (Ajusted OR = 50.13; 95% CI [8.87; 283.50] p = 0.000*) and high triglyceride levels (Ajusted OR = 0.03; 95% CI [0.003; 0.36] p = 0.005*), as type 2 diabetes mellitus potential risk factors, in the present study.
Conclusion: The type 2 diabetes mellitus prevalence in the study population was high. Prevention and control of this disease through early detection are essential.

 

Keywords: 
Type 2 diabetes mellitus; Prevalence; Risk factors; Franceville; Gabon
 
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