Treatment of critical ischemia of the lower extremities

Uktam Safaevich Ismailov 1, Feruz Kasimovich Xomidov 1, * and Nodir Ulug’bekovich Kayumov 2

1 Tashkent Medical Academy, Tashkent, Uzbekistan.
2 Tashkent Pediatric Medical Institute, Tashkent, Uzbekistan.
 
Review Article
Open Access Research Journal of Biology and Pharmacy, 2022, 06(01), 063–070.
Article DOI: 10.53022/oarjbp.2022.6.1.0069
Publication history: 
Received on 17 August 2022; revised on 21 September 2022; accepted on 23 September 2022
 
Abstract: 
Chronic ischemia of the lower extremities (CLLI) remains one of the main socio-economic problems modern medicine. The problem of treating patients with intermittent claudication, despite the rapid development of medical technologies, remains one of the most significant in medicine. The progression of the disease leads to the development of complications such as major cardiovascular events, the development of critical lower limb ischemia (CLLI), as well as amputations, which are disabling diseases. In this article broad notion are summarized on critical limb ischemia, scope of the problem, its treatment and modern approaches for the management of this disorder. Besides, latest clinical trials and study results are stated in order in depth understand the management of the disease.
 
Keywords: 
Atherosclerosis; Dyslipidemia; Peripheral artery disease; Critical lower limb ischemia; Diabetes mellitus.
 
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