Epidemiological Analysis of Toxoplasma Gondii and COVID-19 Seroprevalence in Cases of Pregnancy Loss in Kirkuk City
Department of Microbiology, College of Medicine, University of Kirkuk, Kirkuk, Iraq.
* Corresponding Author
Research Article
Open Access Research Journal of Biology and Pharmacy, 2026, 16(02), 168–181.
Article DOI: 10.53022/oarjbp.2026.16.2.0009
Publication history:
Received on 08 March 2026; revised on 09 April 2026; accepted on 13 April 2026
Abstract:
Background: Toxoplasma gondii is an require intracellular paramecium parasite accompanying a general distribution, contaminating an expansive range of warm-blooded animals and persons. Approximately individual-third of the worldwide community is estimated expected contaminated with T. gondii. In December 2019, Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2) arose and speedily spread worldwide, precipitating Coronavirus Disease 2019 (COVID-19). Both contaminations have existed associated with invulnerable dysregulation and antagonistic pregnancy effects, lifting concerns regarding their linked belongings during pregnancy.
Objective: To examine the partnership between Toxoplasma gondii and SARS-CoV-2 co-contamination and antagonistic gestation outcomes, accompanying particular prominence on the risk of failure and coagulation-connected deformities.
Methods: This case-control study judged serological and biochemical markers, containing cell with hemoglobin sedimentation rate (ESR), creatinine, C-reactive protein (CRP), ferritin, usually from breast dehydrogenase (LDH), aspartate aminotransferase (AST/GOT), alanine aminotransferase (ALT/GPT), antagonistic-Toxoplasma IgM, and anti-Toxoplasma IgG. The calculated limits were analyzed to decide their friendship with gestation consequences among daughters contaminated with SARS-CoV-2 and T. gondii.
Results: Pregnant daughters with evidence of T. gondii contamination and COVID-19 manifested significantly bigger levels of inflammatory and clotting-connected biomarkers compared accompanying control groups. Co-contamination was associated with an raised frequency of unfavorable gestation outcomes, specifically miscarriage. Statistical reasoning disclosed a significant friendship betwixt co-infection rank, elevated instigative stones, and pregnancy obstacles.
Conclusion: Co-contamination with Toxoplasma gondii and SARS-CoV-2 grant permission influence an increased risk of antagonistic gestation outcomes through embellished instigative and coagulation disturbances. These verdicts climax the importance of early protect, careful dispassionate listening, and appropriate management of meaningful wives with doubtful co-contaminations to reduce motherly and before birth complications.
Keywords:
Toxoplasma Gondii, SARS-Cov-2, COVID-19, Gestation Outcome, Failure, Co-Infection.
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Copyright © 2026 Author(s) retain the copyright of this article. This article is published under the terms of the Creative Commons Attribution Liscense 4.0